The Elk1 gene effect on prostate cancer cell line wound healing ability

Abstract

In this study prostate cancer cell line model was used selecting three type of them (Pc3, DU145 & LNCaP) , gene transfecting was done by using the liposome into the cell culture cells then detecting the healing ability by the Wound Healing or (scratching) test that shows clear effect of ELK1 gene in this cells comparing with the control cell transfected with the knock down gene, using for each type of cells 6 repeats ,for each type there was two groups 1st for control ELK1 and the 2nd was knock down or (sh) ELK1, all works was done in Johns Hopkins University / School of Medicine / Pathology Department ( MD, USA)