In Vivo Adaptogenic Lipidomics of Essential Oil Extract of Thaumatococcus Daniellii Leaf

O. Omisope, G.O. Oladipo

Abstract


Thaumatococcus daniellii leaf had been described as being very functional biochemically, due to the essential biomolecules it contains in very regulated quantity. This study was aimed at evaluating the dietary effect of the T. daniellii leaf essential oil on lipid profile in selected tissues. Anti-stress activity was evaluated by lipid profile modulation (HDL, LDL, TRIG. and T. CHOL.). Quantitative and qualitative analyses of essential oil profile of the T. daniellii leaf extract were determined by Gas Chromatography and Mass Spectrophotometer (GC-MS). The GC-MS analyses revealed the amount of some volatile bioactive compounds, with total yield of 0.12% from leaf via hydrodistillation. 0.5ml daily dose of the essential oil revealed effective lipid modulating activity, thus could be of therapeutic importance at this dose.

Keywords: Thaumatococcus daniellii leaf, Essential oil, Lipidomics, Adaptogenic, HDL, LDL, Total Cholesterol, Triglyceride


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ISSN (Paper)2224-3186 ISSN (Online)2225-0921

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