Performance of Cox Proportional Hazard and Accelerated Failure Time Models in the Analysis of HIV/TB Co-infection Survival Data

Abstract

Cox model and accelerated failure time models are widely used in the modeling of survival data for various diseases. This paper compares the performance of these two models viz. Cox Proportional Hazard Model and the Accelerated Failure Time Model using HIV/TB Co-infection Survival data. The study revealed that, the AFT model has the best predictive power compared to the Cox model based on the AIC and BIC values.

Keywords: Cox proportional hazard model, Accelerated failure time model, Cox-Snell residual, HIV/TB Co-infection, CD4 cell count