Compared levels of specific divalent trace elements in hyperlipidemia and hepatitis sera patients

Abstract

Patients with hepatitis infection can also have hyperlipidemia. Sera of both hepatitis (40) and hyperlipidemia (40) were collected from the central lab of Sulaimaniyah-Kurdistan region/ Iraq. Age, sex, duration of infection, medication used and lipid profile using computerized database program, as characteristics information of patients were done.  The levels of Cr, Cu, Zn, Mn, V and Se were determined in sera of both patients and compared with healthy controlled (n=30), using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Hepatitis samples yielded concentration in ppb of (7.34±0.01) Cr, (171.7±2.51) Cu, (138±3.41) Zn, (1.309±0.99) Mn, (184.7±6.12) V and (218.9±3.14) Se respectively, while hyperlipidemia samples yielded concentration (ppb) of (5.22±0.45) Cr, (197.01±2.34) Cu, (160.3±4.01) Zn, (0.068±1.91) Mn, (247.01±0.65) V and (185.5±3.11) Se respectively. Controlled samples reflects the following concentrations (ppm),  (5.324±1.34) Cr, (131.2±4.34) Cu, (216.6±0.83) Zn, (0.024±1.75) Mn, (235.3±0.18) V and (223.2±3.15) Se  respectively.The aim of the study focused on evaluating metal ions physiological role in the body, and as liver was responsible for synthesizing lipid , thus lipid profiles where suggested to be investigated along the study.

Key words: hepatitis, hyperlipidemia, trace elements, ICP-OES technique