The Relationship of Immunoglobulin-E and Oxidative Stress in Iraqi patients with asthma

Zinah Ali, Mufeed Ewadh, Gaylany Abdullah, Hamid Hasan


Asthma is a disease characterized by airway chronic inflammation and bronchial hyperactivity, involving the imbalance of oxidative and antioxidative agents. There is an increased free radical generation and a decreased antioxidant enzyme activity. Fifty subject were enrolled in this study .twenty patients with Asthma . Thirty subjects who are apparently healthy were taken as a control group. Serum IgE was determined by using enzyme- linked immunosorbent assay (ELISA) .MDA was determined by using colorimetric method .Serum levels of IgE was highly  significantly increase in  asthma group compared with control group (p<0.01).A significant positive correlation between IgE and MDA. MDA affect IgE level in patients with Asthma .

Key words : Immunoglobulin – E , Oxidative stress, Asthma

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ISSN (Paper)2224-7181 ISSN (Online)2225-062X

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