Advances in Life Science and Technology
The Relationship of Immunoglobulin-E and Oxidative Stress in Iraqi patients with asthma
Abstract
Asthma is a disease characterized by airway chronic inflammation and bronchial hyperactivity, involving the imbalance of oxidative and antioxidative agents. There is an increased free radical generation and a decreased antioxidant enzyme activity. Fifty subject were enrolled in this study .twenty patients with Asthma . Thirty subjects who are apparently healthy were taken as a control group. Serum IgE was determined by using enzyme- linked immunosorbent assay (ELISA) .MDA was determined by using colorimetric method .Serum levels of IgE was highly significantly increase in asthma group compared with control group (p<0.01).A significant positive correlation between IgE and MDA. MDA affect IgE level in patients with Asthma .
Key words : Immunoglobulin – E , Oxidative stress, Asthma
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ISSN (Paper)2224-7181 ISSN (Online)2225-062X
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