Animal Feeding Trial on Formulated Rat Diet

Abstract

This research focused on the feeding trial of formulated feed ration for albino rats and to know the effect of this feed on the rats, compare with those of control feed (Top feeds) by carrying out some analyses such as biochemical, haematological, and growth performance of the rats. The rats (16) were allocated into four dietary treatment groups and fed on a short term study with diet containing different proportions of feed. The outcome demonstrated or revealed that Group II had a mean weight of 131.7, PCV of 51 ± 2.2, WBC of 12727 ± 89.9 X 10³ mm, AST of 181.4 ± 2.7u/l, ALT 128.3 ± 2.9 u/l, Total protein of 61 ± 1.4 and Cholesterol of 2.9 ± 0.1 g/dL had a positive effect on the growth performance of the rats when compared to the control group which has mean weight of 161.7, PCV of 50.3 ± 2.1, WBC of 12317 ± 164.99 X10^3/ mm, Cholesterol of 2.7 ± 0.2, Total protein of 61.2 ± 1.0 g/dL, ALT of 132.5 ± 6.6u/l, AST of 180 ± 1.7. But Group 1 with mean weight of 124.0, PCV of 52 ± 1.1, WBC of 15586 ± 241.2 X 10^3/ mm, Cholesterol of 6.4 ± 0.6, Total protein of 74.9 ± 6.4 g/dL, AST of 182.1 ± 3.0u/l, ALT of 125.8 ± 2.7u/l has an increased in WBC which can lead to inflammation or infection while In Total protein can leads to liver disease due to high content of groundnut; while Group III with mean weight of 120.0, PCV of 51.4±1.6, WBC of 14190 ± 313.7 X10^3/ mm, Cholesterol of 3.6±0.4, Total protein of 81± 4.8 g/dL, AST of 183.4 ± 3.2u/l, ALT of 130.1 ± 2.6 which also increase.ALT and AST levels in Group l and III suggested liver damage due to increased in their blood serum. This finding strongly suggests the use of Group II’s formulated feed diet as a substitute for rat feed.

Keywords: Wistar rats, formulated diet, feeding trial.