Inhibitory effect of new ligand 2, 3, 5, 6, 0, 0, 0, 0- tetra acetic acid-L- ascorbic acid on pathogenic bacteria

Abstract

The inhibitory effect of new product (2, 3, 5, 6, 0, 0, 0, 0- tetra acetic acid-L- ascorbic acid)(V-C-4Ac) on growth of different types of pathogenic bacteria was investigated. Different concentrations were prepared from (V-C-4Ac) , (1%, 3%,  4% and 5%) nearly completely inhibited the growth of Streptococcus pneumoniae and Streptococcus agalactiae after 24 hrs incubation, and the same range of concentrations did not inhibit the growth of Streptococcus mutans, Klebsiella pneumonia and Proteus mirabilis. Also, this study shows  low effect of new ligand in the growth of Staphylococcus aureus and E. coli in high concentration (5%) after 2 hrs incubation.

Keywords: L- ascorbic acid, New ligand synthesis (V-C,4Ac) , Antibacterial effect.