Comorbid Status Evaluation of Some Serum ionic content in Glucose excess, Hypertension and obesity.

Abstract

Changes in the Levels of serum ion have earlier been reported in some pathophysiological conditions. We studied these changes in the triad of Glucose Excess, Hypertension, obesity and in a comorbid state. We evaluated calcium (Ca²⁺), magnesium (mg²⁺), lithium (Li), zinc (Zn²⁺), phosphorus (P₀₄), glycated haemoglobin (HbA1c) and hydrogen ion concentration (P^H) along with some other parameters. Adopting spectrophotometric, flame photometric and conductimetric methods parameters were analyzed. Using two way analysis of variance values obtained were statistically evaluated. The conditions presented varying degrees of elevation of Ca²⁺, Zn²⁺ and HbA₁C. Mg²⁺, P_04-, K⁺ and P^H however correlated inversely with HbA1c. Comorbid condition show a trend in which most of the parameters were slightly reduced. Values obtained is suggestive of these ions  affecting acid base balance and homestasis.

Keywords: ionic content, Glucose excess, hypertension, obesity, comorbid.

DOI: 10.7176/ALST/99-04

Publication date:December 31^st 2023