An Assessment of Medicinal Cocus Nucifera Plant Extracts as Natural Antibiotic Phytotherapies.

Abstract

The natural antibiotic phyototherapeutic value of Cocus nucifera were screened against five bacteria isolates (Staphylococcus. aureus, Escherichia. coli, Streptococcus. pneumoniae, Proteus. mirabilis and Pseudomonas. aeruginosa) using the agar-well diffusion method. The root extracts were screened for antibacterial activities at concentrations of 100ml/ml. The antibiotic value of the extract against the bacterial strains was indicated by the appearance of clear zone of inhibition around the wells. The percentage yield for the various solvent was found to range between 17.32 – 32.60 with ethanol having the highest value (35.60). The susceptibility of the organism to the antibiotic effect of the extract vary among the different organism tested. The highest zone of inhibition was recorded in Escherichia coli (13.08±0.14). While the least was observed in Pseudomonas aeruginosa (0.08±0.00). Comparison of the antibiotic effect of the extract with some commercial antibiotic. Gentamycin, penicillin and Trimethoprin showed that the commercial antibiotic was found to be more effective in inhibiting the growth of the tested bacterial isolates than the Cocus nucifera extract. Phytochemical screening of the extract revealed the presence of saponin, tannis, Glycosides, Alkaloids and flavonoids which has been associated with the antimicrobial activities of several herbs. Thus, these preliminary results support the folkloric claims of cocus nucifera preparations are effective against some disease.

Keywords: Natural antibiotic the Phytoetherapies, Cocus nucifera, Phytochemical. Corresponding authors: email: immaugo@yahoo.com.