Evaluation of the coexpressed gene network of DREB2A

Abstract

Different proteins in the cell perform their function in a unified way, interacting with the other proteins involved in completion of the particular metabolic pathway. The information about a single protein estimated from an organism subjected to a particular treatment will reveal only part of the process. To understand the process completely it is very essential to have an assessment of the different proteins linked together in different pathways and also the level of expression of different genes under different conditions. The coexpressed genes reveal the part of the genome which is intricately involved in carrying the process being studied.

The network of coexpressed genes with DREB2A was analyzed. DREB2A is involved in different processes related to drought and salt stress. Out of the genes coexpressed with it, At1g16030 is Hsp70b/ Heat Shock Protein 70B, and is reported to be involved in virus attack and in protective processes under heat stress. Similarly At2g26150 was also observed to be closely networked with DREB2A, and is a member of heat stress transcription factor. The information from the coexpressed network of DREB2A shows that the interacting proteins play important role in protection of plants from pathogen attack and also in protecting the protein repertoire of the plant from denaturation when it is subjected to salt and heat stress. Copyright © www.iiste.org

Keywords: DREB2A, Heat shock protein, transcription factor, coexpressed genes