Extract of Sesamum Indicum Seeds on the Glycogen Profile of the Liver of Adult Wistar Rat

Abstract

The aim of this work was to evaluate the effect of seeds extract of Sesamum indicum on the histology liver of adult Wistar rats. Thirty Wistar rats weighing between 150-180g were divided into three groups of ten each; control group A received distilled water, experimental B and C received 200mg/kg and 400mg/kg of the seed extracts respectively. The extracts were administered for two weeks, at the end of which the animals were sacrificed; livers were removed and processed for Haematoxylin and eosin (H&E) paraffin sectioning and staining method while the serum was used for liver enzyme assay. From the results obtained, the administration of ethanolic seed extract of Sesamum indicum caused no obvious structural derangement in the organ There were no adverse effects on glycogen distribution.

Keywords: Liver, Wistar rats, Sesamum indicum, glycogen