Comparison of Mild Cognitive Impairment Between the Older People with Diabetes Mellitus and without Diabetes Melitus

Abstract

Dementia is a disease that is most common and most damaging in the elderly. Nearly 4.6 million new cases are found each year and is found in the number doubled every 20 year and it is estimated there are 81.1 million people in the year 2040. (Velayudhan L, Poope M, Archer N, Proitsi G, Brown R, lovestone S.(2010)). Luchsinger and colleagues found that diabetes mellitus have an increased risk propensity on samples were non-amnestic mild cognitive impairment. The risk of mild cognitive impairment caused by diabetes mellitus was 8.8% for the entire sample and is higher in African-American population of 8.4% and a population Hispanik11,0% compared with the Non-Hispanic whites were 4.6% reflecting prevalence of diabetes mellitus in minority populations in the United States. (Luchsinger JA, Reitz C, patel B, Tang MX, Manly JJ, Mayeux R.(2007)).This study was a cross sectional study. Place of research: Geriatric Clinic, Clinic of Internal Medicine Endocrine SMF RSUP.H.Adam Malik and Lions Club of Medan City Polyclinic jl. Anggrung no.5. Periode 10 February 2011 until May 2011. Any patients who met the inclusion and exclusion criteria were included in the study will be done when blood sugar levels which will then be followed by a fasting blood sugar levels in the next day and on the same day the patient will psychiatric interview examination. All data collected will be analyzed further. Results from this study, of the 124 samples obtained, there were 38 samples (30.6%) with a normal MMSE interpretation, 24 samples (19.4%) with interpretation of probable cognitive impairment and 62 samples (50%) who had a definite interpretation of cognitive impairment . By chi square analysis found as many as 38 people who had a normal MMSE score interpretation consisted of 73.7% men and 26.3% women. of 24 samples of group interpretation MMSE score, probable cognitive impairment found 41.7% of men and 52.3% women and 62 samples of definite cognitive impairment found 38.7% of men and 61.3% of women with a figure of significance 0.002 (p <0.05). With Kolmogorov- Smirnov analysis can be seen that there are 30 samples or 24.19% of the sample who did not have diabetes mellitus who had a probable interpretation of MMSE cognitive impairment and 27 samples or 21.77% of the sample who had diabetes mellitus who also had MMSE interpretation, probable disturbance cognitive significance with the number 0.269 (p> 0.05). In the study showed that the elderly can experience mild cognitive impairment and diabetes mellitus have a role in the incidence of mild cognitive impairment in the elderly.

Keywords: cognitive impairment, diabetes mellitus