Epidemiological and Virological Study of Hepatitis C Virus Infection in Hemodialysis (Case of Six Centers) in Morocco

Abderrahim Foullous, Sanaa Mahmal, Ali Asdadi, Naoufal Mtioui, Fatima Ouaddi, Selma siham Elkhyat, Ghislaine Medkouri, Fatiha Lazaar, Abdelouahab Bennani, Abderrahman Hammoumi


The purpose of this study was to determine the prevalence of viral RNA and HCV genotypic profile 6 hemodialysis centers in Casablanca. A total of 630 patients were included in this survey, 194 patients of them  have antibodies antiHCV + ; then the prevalence is 30.79% , indeed search for viral RNA by PCR  in this population  was detected in 105 patients , also, the  prevalence of viral RNA is 54.1%. The study of genotypic profile in this population showed the following distribution: the most prevalent genotype is genotype 1: subtype 1a was found in 19 patients (18.09%); subtype 1b was found in 49 patients either (46, 66%); genotype 2a / 2c in 27 patients (25.71%); genotype 2 in 5 patients (4.76%), 4h genotype was detected in one patient with a frequency of 0, 95%, genotype 4 was found in 4 patients with a frequency of 3, 80%. Indeed, extensive studies and large scale is needed to understand the epidemiology of HCV.

Keywords: Hepatitis C virus, Prevalence, Genotype, Public health, Morocco genotypes in hemodialysis.

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ISSN (Paper)2224-3208 ISSN (Online)2225-093X

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