The Effects of Crude Extracts of Ginger (Zingiber officinale) On Some Lipid Profile Parameters In High Fat Fed Rats.

Abstract

The effects of various doses of ginger (Zingiber officinale) on lipid profile parameters of rats fed high fat diets for six (6) weeks were determined. Results obtained shows that the administration of crude extract of ginger for two weeks at 200mg/kg body weight significantly (p<0.05) reduced the level of cholesterol, triglyceride, low density lipoproteins (LDL) and increase High density lipoproteins (HDL) (69.15±4.69, 100.00±3.91, 6.90±1.96, 20.00±0.78 and 41.05±2.99) respectively compare to value obtained in rats fed normal diet (71.50±7.75, 120.63±4.54, 20.85±1.18, 18.32±0.90 and 26.12±4.82) respectively. This shows that consumption of ginger at higher doses may be beneficial in reducing some lipids profile parameter and body weight which could aid in preventing cardiovascular diseases.

Keywords: Lipid profile, Zingiber officinale, cardiovascular disease, High fat diet