Antibiotics Sensitivity Pattern of Bacterial Isolates at the Health Centre, Adekunle Ajasin University, Akungba-Akoko, Ondo State

Abstract

Background: This study was a four years retrospective review of the records of the routine microbiological, culture and sensitivities of different samples (urine, aspirates, stool, semen, high vaginal swabs etc.) collected from patients(mainly staff and students) that attended the Health Centre of Adekunle Ajasin University, Akungba-Akoko for treatments of bacteria related infections.Methodology: An ethical clearance was obtained from the committee saddled with the responsibilities with the assurance of the confidentiality of the identity of the patients. Clinical Laboratory records of 1008 cases of Samples taken through standard procedures were selected for the study to examine them for spectrum bacterial isolates, age and sex distribution of cases of infections and the antibiotic susceptibility pattern of isolates.Results: Out of 1008 samples, 437(43.4%) did not give significant bacterial growth, while 571 (56.6%) gave bacterial growth of different species. Staph aureus has the highest occurrence of 22.4%, followed by E. coli 15.5% and Salmonella spp has the least. The antibiotics with very good in vitro sensitivity include the Quinolones, Nitrofurantoin, Gentamicin, Erythromycin Tobramycin and Clindamycin. Paradoxically Ceftriaxone did not show a remarkable sensitivity pattern.Conclusion: The most common bacterial isolates are Staphylococcus aureus and E. coli and the antibiotics identified as having the highest in vitro sensitivity pattern are recommended for first line management of septicaemia infections where they are indicated, in blind therapy.

Keywords: Bacterial isolates, Antibiotic sensitivity, AAU, Akungba-Akoko.