Seroprevalence study of IgG and IgM Antibodies to Toxoplasma, Rubella, Cytomegalovirus, Chlamydia trachomatis and Herpes simplex II in Pregnancy women in Babylon Province

Abstract

In this work 180 blood samples was collected from pregnant women in Babylon province, Babylon maternity and children hospital from October/2008 to April/2009. It revealed that TORCH infections was; Cytomegalovirus formed (CMV) 57.2% followed by Toxoplasma gondii 55.5% Rubella 53.9%, Herpes simplex II 28.9% and Chlamydia trachomatis 24.4%.

Seroprevalence of Toxoplasma, Rubella, CMV, Chlamydia trachomatis and Herpes IgM Antibodies according to various obstetric losses showed that Abortions happened in all causes with high percentage (Over than 30%) except Herpes infections (less than 6%), while congenital anomalies and premature delivery formed high ratio with some different in some cases. Neonatal deaths are very low under 1% except in CMV infections which formed 4.9%.

Distribution of age with type of infection according IgM Antibodies to Toxoplasma, Rubella, CMV, Chlamydia trachomatis and Herpes simplex revealed that major age group for infection was between <20 to 40 years which formed more than two third of all infection cases.

Residential distribution with type of infection according IgM Antibodies shows that most infection occurred in rural area (over than 50% in all agents) except in Herpes simplex infections which formed 82.7% in urban area.

TORCH (Toxoplasma gondii, Rubella, Cytomegalovirus and Herpes simplex) infections with incidence of abortion in pregnant women in this study revealed that First trimester was the highest ratio of infection than other two trimesters.