Autologous Adipose Stem Cells Use for Skin Regeneration and Treatment in Humans

Abstract

There is growing evidence that adipose stem cells contribute to the restoration of tissue vascularization, and have a potentially large therapeutic effect in the field of regenerative medicine. The purpose of this study was to assess the clinical effectiveness of lipoaspirate transplantation on the treatment of skin lesions in humans. This study began with surgical procedures in 2009 followed by a follow-up plan for 4 months. Twenty clients underwent therapy for skin lesions and follow-up. Adipose derived stem cells can promote human dermal fibroblast, proliferation, and re-epithelialization of cutaneous wounds, rejuvenation of the aging skin and related skin lesions. These stem cells replenish dying cells, and have the capacity to regenerate new tissues. Adverse events including pain, swelling and allergy were minimal. All participants expressed their satisfaction of the results. This surgical procedure is a low-invasive therapeutic approach that can resolve the problem of depressed skin, skin lesions, and wrinkles. Adopting this procedure decreases the cost of skin care, and improves client’s long-term outcome. Furthermore, it facilitates cell-mediated skin repair and regeneration.

Keywords: Adipose stem cells, Lipoaspirate, skin diseases.