Clinicopthological Characteristics of Hodgkin Lymphoma in Jordan

Abstract

The aim of our study is to describe the clinical and pathological characteristics in patients with Hodgkin lymphoma , also to measure the prognosis of this disease between our patients ,This retrospective study done  at ‘‘king Husain Medical Centre in Amman-Jordan, All patients diagnosed with Hodgkin lymphoma was included, 92 patients diagnosed with the disease between January 2010 and January 2013. No patient was excluded. Demographic and clinical characteristics of the patients included are .the age, sex, date of diagnosis, presenting symptoms, group of LN enlarged, response to treatment assessed by PET scan post 2 cycles and at the end of treatment. Results" 59 (61.7%) of patients was Male and 33 was female ( 35.9%) , Age of patients ranged from 19 years old to 60 years with two peaks In 2^nd and 4^th decade, Cervical LN was the commonest lymph node enlarged at presentation in 87% of patients ,43.5 % of our patients was staged as stage 4 , B symptoms was documented in 26 of patients 28% , Extalymphatic disease was found in 40 patients most common involvement was lungs in 17 patients, Nodular sclerosis was the commonest histopathology in 73%, ,Complete remission with follow up PET scan was observed in 88% of patients, CR was noted more in young age group .Conclusion "Hodgkin lymphoma one of uncommon malignancy in Jordan, with epidemiology same as developed countries ,but the second age peak is younger than western countries, even most of patients presented with advanced stage disease it carry a very good prognosis with treatment and regular follow up.

Keywords: Lymphoma, Hodgkin, Clinicopathological.