In-vitro antioxidant activities, anti-nociceptive and neuropharmacological activities of Polygonum hydropiper

Abstract

In the present study in-vitro antioxidant activities, anti-nociceptive assessment and neuropharmacological study of the leaf extract of Polygonum hydropiper was performed. In-vitro antioxidant activity of the extracts of P. hydropiper was performed using DPPH free radical scavenging, cupric reducing antioxidant capacity, total antioxidant capacity, total phenol and total flavonoid content determination assays; anit-nociceptive activity was done by using acetic acid induced writhing method and neuropharmacological activities were assessed by  open field test and swimming test. The plant’s leaf extracts exhibit potent antioxidant activities; significant anti-nociceptive activity and neuropharmacological activity.

Keywords: Polygonum hydropiper, in-vitro antioxidant activities, anti-nociceptive activity, neuropharmacological activities.