FREQUENCY OF CATHETER INDUCED THROMBOSIS IN PATIENTS WITH END STAGE RENAL DISEASE (ESRD) ON HEMODIALYSIS

Abstract

Objective; To determine the frequency of catheter induced thrombosis in patients with end stage renal disease (ESRD) on hemodialysis. Material and Methods; All the cases (86) undergoing hemodialysis were recruited from Department of Medicine, Nishtar Hospital Multan, Pakistan. Double lumen hemodialysis catheter was inserted by a senior consultant. Color Doppler sonography was done at the 6^th day of placement of catheter and presence of thrombus was noted in the study proforma. History was taken for hypertension, smoking, family history and previous history of thrombosis. Results; Of these 86 study cases, 51 (59.3 %) were male patients and 35 (40.7%) were female patients. Mean age of our study cases was 45.62 ± 8.44 years. Of these 86 patients 28 (32.6%) were diabetic, 35 (40.7%) were hypertensive, 34 (39.5%) were smokers and 07 (8.1%) had previous history of thrombosis. Mean duration of catheter placement was 81.62 ± 41.67 days and mean duration on hemodialysis was 22.36 ± 10.43 months. Majority of our study cases i.e. 65 (75.6%) had to undergo hemodialysis three times in one week. Catheter related thrombosis was noted in 29 (33.7%) of our study cases.

Conclusion; Frequency of catheter-related thrombosis was high in patients with end-stage renal disease (ESRD) in our study. Thrombosis in ESRD patients was significantly associated with male gender, age, duration of catheter placement and duration of hemodialysis.

Keywords; End-stage renal disease, catheter, thrombosis.