Association of Depression and Anxiety with Missed Miscarriages

Abstract

Objective: To find out the Association of Depression and Anxiety with Missed Miscarriages.

Study Design: cohort study / observational study

Place and Duration of Study: Study was performed in department of obstetrics and gynecology Nishtar Hospital Multan from January 2017 to January 2018.

Methodology: We include the women diagnosed with missed miscarriage in observational group and the pregnant woman who are going to deliver normally as control group. Data of the each patient include body mass index, age, education level, occupation, planned pregnancy, health status before the pregnancy, information regarding pregnancy, exercise status of the patient before pregnancy and folic acid supplementation. To check the grade of anxiety and depression of the patient we used the Self-Rating Anxiety Scale (SAS) Center Epidemiological Studies Depression Scale (CES-D) respectively. Quantitative data was compared by applying Students T test and Chi-square test was applied on nominal data. Computer software SPSS version 23 was used to statistically analyze the data. P value of less than or equal to 0.05 was taken as significant.

Results: Life Events Scale for Pregnant Women (LESPW) was 220.08±90.58 and 137.04±56.59 in the observation and control groups respectively, difference being statistically significant (p<0.001).  SAS was 43.25±9.60 in the observation group and 38.24±9.65 in the control group (p=0.002). CES-D score was significantly high in the observation group in comparison with the control group (p<0.001).

Conclusion: In our study we came to the conclusion that the negative emotions like anxiety and depression causes an increase in the rate of missed miscarriages

Keywords: Anxiety, Depression, Missed miscarriage