Antibacterial Activity of Aluminum Potassium Sulfate and Syzygium Aromaticum Extract Against Pathogenic Microorganisms

Abstract

Natural products have been used for centuries in treating human disease. The present study aimed to determine the antibacterial ability of aluminum potassium sulfate (alum) and Syzygium aromaticum (clove) extract against different types of pathogenic bacteria in scientific way. Antimicrobial activity of crude extract from two commonly used medicinally materials, alum and clove were evaluated against four microorganisms over different concentration (10, 20, 30, 40 and 50) w/v %. Minimum inhibitory concentration (MIC) and the diameter of inhibition zone were determined by in vitro bioassay using agar well diffusion method against S. aureus, S. epidermidis, E. coli, Klebsiella pneumonia. The two medicinal materials exhibited antibacterial activity and inhibition growth of gram positive and gram negative bacteria isolated from different sites of infection. The inhibition effect of these extracts compared with standard antibiotics cefotaxime. In conclusions, the results of present study revealed that the alum and clove could be used as natural antimicrobial in different ways.

Keywords:Alum, clove, Syzygium aromaticum, S. aureus, S. epidermidis, E. coli, Klebsiella pneumonia, cefotaxime