Histological Study of Aqueous Extracts Leek Allium porrum L. in Female Reproductive System of Laboratory White Rats

Abstract

The aim of this study is to evaluate The effect of aqueous extracts of Allium porrum leafs on Reproductive system in female albino rats.

This study was conducted in laboratories of  physiology and chemistry which belong to the College of Veterinary Medicine / University of kufa and laboratory of  physiology of Faculty of Dentistry / University of kufa for period from 17/12/2013 to 25/11/2013 .It was used female white rats giving deferent dosages with deferent concentration (400,800) mg/kg for 20 days. It shows significantly decreased (p? 0.05) In the weights of ovaries of white female rats for both concentrations (400,800) mg/kg and the concentration 800 mg/kg is the more significant in reducing the weights of the ovaries comparing with control group . It also shows significant increase (p? 0.05) in the weights of uterus for both concentrations 400,800 mg/kg and the concentration 800 mg/kg is the more significant in increasing the weights of the uterus comparing with control group.

The histological study showed significant decrease (p? 0.05) in the number of the primary , secondary follicle and graffian follicle after dosing for both concentrations and duration , the reveals significant increase (p? 0.05) in the thickness of endothelium of the uterus in the female white rats after dosing for treatment by this was 800 mg/kg for period of 20 days compared with the control group.

In short , the aqueous of leek extract acts as anti- fertility in white female rats through its negative effects on the genitals ovaries and uterus, Effect of aqueous of leek extract for two concentration on the weight of ovaries and uterus , Also effect in the numbers of primary , secondary and graffian follicles and the effect of aqueous of leek extract in the thickness of endometrium and myometrium.

Keywords : Allium porrum , Reproductive system, Albino Rats.