The Antibacterial Activity of Dimethyl Sulfoxide (DMSO) with and without of Some Ligand Complexes of the Transitional Metal Ions of Ethyl Coumarin against Bacteria Isolate from Burn and Wound Infection

Abstract

Antibacterial activities (in vitro study)  of Dimethylsulfoxide (DMSO) with and without of some ligand complexes of the transitional metal ions of ethyl coumarin were carried out with the help of agar well diffusion method technique against four human pathogenic bacteria isolation from burn and  wound infections , Observed through the results and the presence of DMSO obvious effect on the bacterial species under study, When melting ligand complexes of the transitional metal ions of ethyl coumarin in DMSO and tested on bacteria see a significant increase in the diameters of the inhibition of the growth of bacteria, compared with the use of DMSO alone, it has observed that the complex 3and 4 was more active than the others. The complexes 1,2,5,6  also has showed substantial antimicrobial activity. Furthermore The staphylococcus aureus bacteria was more types of bacteria sensitive to the effect of the complex studied .

Keywords: Antimicrobial activities, Dimethylsulfoxide (DMSO), human pathogenic bacteria, burn & wound infections .