Isolation and Characterization of Estra-17-propoxy, 3/, 4/ – dimethoxy – 3yl benzoate from the leaves of Spondias mombin linn

Abstract

Spondias mombin linn is one of the traditional medicinal plants with a lot of potential, valuable and untapped resource of active drugs for treating diseases. It is used in Nigeria for the treatment of cough, wounds, inflammations, diarrhoea, dysentery, haemorrhoids and gonorrhoea. A chemical investigation of the bioactive constituents of the leaves of Spondias mombin linn resulted in the isolation of a new steroid, Estra-17-propoxy, 3/, 4/ – dimethoxy – 3yl benzoate. The structure was elucidated using a two Dimensional spectroscopy, NMR (1H, 13C), IR and MS spectroscopy data. Keywords: Spondias mombin, diuretic, gonorrhoea