Estimation Arginase Activity in the Serum of Uterine Fibroid Females and its Relationship with Other Parameters

Abstract

The research includes a clinical study of Arginase and its relation with uterine fibroid. The normal value of arginase activity in female serum was found to be (0.52 ± 0.02 IU/L) in healthy group at age (35-55) years. The study also showed a highly significant increase in arginase activity (7.99 ± 0.23 IU/L) in serum of uterine fibroid patients group at (35-55years) in comparison to healthy.The results also indicated a highly significant increase in the level of progesterone, estradiol, prolactin, peroxynitrite and malondialdehyde in patients group. While a highly significant decrease in concentration of adiponectin in patients group was found in comparison to healthy.

Keywords: Arg , Adipo Q, PRO, E₂, PRL, Peroxynitrite, MDA.

Abbreviations: Arg, Arginase; Adipo Q, Adoponectin; PRO, Progesterone; E₂, Estradiol; PRL, Prolactin; MDA, Malondialdehyde.