Evaluation of Paroxonase and Interleukin-35, in Iraqi Female Patients with Multiple Sclerosis (MS) Disease

Abstract

The present study was carried out to evaluate the effective role of PON and Il- 35 in serum female patients  with multiple sclerosis (MS). In this study , 30 females were enrolled , the duration of the disease was from 3 months to 2 years (Group2 G2) were taken from Baghdad teaching hospital through the period from April-2013 to – Dec.2013. They were compared with 30 apparently healthy females with the same range of age (20 to 30) years (Group 1 G1) .Results Showed high significant decrease of PON in Group 2 compared with Group 1 , while high significant increase in IL- 35 was noted in Group 2 compared with Group 1 .Besides , high significant positive Correlation was observed between PON and IL- 35 in both of Group 1 and Group 2. It was conclude that PON and IL -35 may be used as a clinical marker In Multiple Sclerosis disease.

Keywords: Paroxonase, Multiple Sclerosis, Interleukine -35.