THYROXINE LEVELS IN DIABETIC AND NON-DIABETIC PATIENTS

Abstract

Thyroxine levels in diabetic and non-diabetic patients in Nigeria are not well described. To determine the concentration of thyroxine in diabetic and non-diabetics fasting blood sample from 45 diabetics and 45 non-diabetic patients were analysed. Total thyroxine (T₄) concentrations (11.50 ± 3.50) in diabetic males between 1-29 years of age were significantly (p? 0.05) higher than that of the non-diabetic males (6.75 ± 0.47), concentrations (8.50 ± 0.29) in diabetic males between 30-59 years of age were lower than that of non-diabetic males (8.71 ± 0.42) and concentrations (7.60 ± 0.68) in diabetic males between 60 years and above, were also lower than that of non-diabetic males (8.60 ± 0.25). T₄ concentrations (9.00 ± 0.31) in diabetic females between 1-29 years of age were higher than that of non-diabetic females (7.33 ± 0.62), concentrations (8.56 ± 0.34) in diabetic females between 30-59 years of age were also higher than that of non-diabetic females (8.30 ± 0.47) and concentrations (6.50 ± 0.50) in diabetic females between 60 years and above, were lower than that of non-diabetic females (6.67 ± 0.33). Note that values are mean and standard deviations.

Keywords: Thyroxine, diabetics, non-diabetics, fasting blood glucose, thyroid stmulating hormone, hypothyroidism, hyperthyroidism.