The Role of Transcription and Gene Expression in the Evolution of T-Cell Lymphocytes

Abstract

This research will concern on discussing transcription and gene expression impact in the T-Cell lymphocytes evolution, by discussing the composition of the lymphatic system, specifically the receptors of the T-cell lymphocytes. As well as, both transcription and gene expression will be discussed.To achieve that aims, Inductive Approach will be used by collecting information from different studies until reaching the final results.The study found that decreasing of LEF-1 does not affects the evolution of the Thymus, but affects non-lymphatic parts, deteriorates severely and leads to death.   But, decreasing of TCF-1 transcription factors affects the differentiation of thymus cell, resulting in a pool of cells with its immature single positive CD8⁺ SP/ CD4⁺ SP, which migrate to different parts of the body.