The Durability of Immunity to SARS-COV-2 Infection in Man

Abstract

The durability  of covid-19 immunity in man was  being  explored  in this opinion. Criteria for determination of post-recovery protective immunity were  suggested. Current published information indicated that it may last for three to six months in accordance with the sero-conversion and sero-prevalence  actual studies. While according to memory B and T cell studies ,it was demonstrated  that both of  memory B and memory T cells can be detected up to eight months in post recovery  period  of  mild to critical cases  of covid-19  and up to 12 months in a retrospective study on large scale seasonal circulating coronavirus human re- infection incidence .Though the extent to which  post-recovery  protective B and T cell  immunity operate to re-infection still remain to elucidated. Factors affecting the duration of herd immunity to sars-cov-2 were  suggested. basis.

Keywords: Covid-19,  coronovirus  durability  ,memory cells, post-recovery ,protective,  sero-conversion ,sero-prevalence.

DOI: 10.7176/JNSR/11-22-06

Publication date: November 30^th 2020