Antibacterial Acivity of Tetrahydropentagamavunon-0 (THPGV-0) and Tetrahydropentagamavunon-1 (THPGV-1)

Abstract

THPGV-0 has antibacterial activity against S. aureus and B. subtilis at concentration 5 mg/mL and no activity againts E. coli until concentration 10 mg/mL. THPGV-1 has antibacterial activity againts S. aureus, E. coli, and B. Subtilis at concentration 0.5 mg/mL, 1 mg/mL and 0.5 mg/mL. While PGV-1 has activity at concentration 0.5 mg/mL, 5 mg/mL and 1 mg/mL against S. aureus, E. coli and B. Subtilis but with smaller zone of inhibition. THPGV-1 is better antibacterial agent than THPGV-0. THPGV-1 is a better antibacterial agent compared to PGV-1.

Keywords: antibacterial activity, tetrahydropentagamavunon-0 (THPGV-0), tetrahydropentagamavunon-1 (THPGV-1), Pentagamavunon-0 (PGV-0) , Pentagamavunon-1 (PGV-1)