Mathematical Modelling of Transmission Dynamics of Anthrax in Human and Animal Population.

Abstract

Anthrax is an infectious disease that can be categorised under zoonotic diseases. It is caused by the bacteria known as Bacillus anthraces. Anthrax is one of the most leading causes of deaths in domestic and wild animals. In this paper, we develop and investigated a mathematical model for the transmission dynamics of the disease. Ordinary differential equations were formulated from the mathematical model. We performed the quantitative and qualitative analysis of the model to explain the transmission dynamics of the anthrax disease. We analysed and determined the model’s steady states solutions. The disease-free equilibrium of the anthrax model is analysed for locally asymptotic stability and the associated epidemic basic reproduction number. The model’s disease free equilibrium has shown to be locally asymptotically stable when the basic reproductive number is less than unity. The model is found to exhibit the existence of multiple endemic equilibria. Sensitivity analysis was performed on the model’s parameters to investigate the most sensitive parameters in the dynamics of the diseases.

Keywords: Anthrax model, Basic reproductive number, Asymptotic stability, Endemic equilibrium, Sensitivity analysis.