Synthetic, Spectroscopic And Antibacterial Studies Of Fe(II),Co(II),Ni(II),Cu(II),Zn(II),Cd(II)and Hg (II),Mixed Ligand Complexes Of Saccharin And Amoxicillin(antibiotics)

Abstract

Mixed  ligand complexes of bivalent metal  ions, viz; M= Fe(II),Co(II),Ni(II),Cu(II), Zn(II), Cd (II),  and Hg(II) of  the composition Na2[M (Amox)(Sac)3] in 1:1:3  molar  ratio,  (where  Amox = Amoxicillin tryhydrate (C16H19N3O5S.H2O) and Sac = Saccharine(C7H5NO3S) have  been  synthesized and  characterized  by  repeated  melting  point  determination, Solubility, Molar conductivity, determination  the percentage of  the metal  in  the  complexes  by  flame(AAS), FT-IR, magnetic  susceptibility  measurements  and  electronic  spectral  data.  The   ligands and  their metal complexes have been screened for their biological activity against selected microbial strains (gram +ve) and (gram -ve).

Key words:( Amoxicillin antibiotics, Saccharine, mixed ligand) Complexes, Antibacterial activities, and spectral studies