Pharmacokinetic Interactions of Rosuvastatin: A Review

Abstract

Rosuvastatin was claimed a “super-statin” to lower the LDL cholesterol comparing with other statins. An excellent benefit-risk profile of Rosuvastatin makes it more acceptable to treat dyslipidemia.   Safety profile is also comparable with other marketed statin. This statin is widely prescribed to treat hyperlipidemics in combination with other drugs. Interactions with other co-prescribed drugs might potentiate or lower its therapeutic effectiveness.

This review accentuates the origin of rosuvastatin in the family of statins and highlights the various interactions specifically pharmacokinetic interactions with other drugs that are commonly prescribed in its combination.

Keywords: Rosuvastatin, Interactions, Statins, Hyperlipidemia