Comparison Between the Effect of Clomid and Pregnyl on Sperm Concentration, Percentage of Sperm Progressive and Percentage of Normal Sperm Morphology.

Abstract

The most common abnormal parameters that view in seminal fluid analysis in infertile men are low sperm concentration, decrease in percentage of sperm progressive and decrease in percentage of normal sperm morphology, which constitute more than 80 % of the causes of male infertility, and due to presence of variation between several drugs that use to treat the infertility, the current study worked comparison between clomid and pregnyl to differentiate what is the best to use it where can be treat more than cause of these reasons. Methods: Fifty patients they divided into two groups, each group composed of 25 patients. From all patients in the two groups takes two samples of seminal fluid  one before treatment and the other after three months of treatment to measure the sperm concentration, percentage of sperm progressive and percentage of normal sperm morphology. Results: The first group of the patients treated by clomid they showed significant improvement in sperm concentration (P = 0.000), percentage of sperm progressive       (P = 0.012)  and percentage of normal sperm morphology (P = 0.036). While the patients in the second group who treated by pregnyl they showed significant enhancing in sperm concentration only (P = 0.002).

Keywords: Spermatogenesis, Sperm count, Sperm progressive, Sperm morphology, Clomid, Pregnyl