Antibacterial Activity of 2- (2-Hydroxy phenylimino) Acetic Acid

Abstract

The ability of 2-(2-hydroxy phenylimono) acetic acid [2-(2- HP-AA)]  to inhibit growth of different types of pathogenic bacteria was investigated.Different concentration were prepared from this chemical compounds( 40 mM ,50 mM and 70 mM).

E.coli, staphylococcus aureus and streptococcus agalactiae nearly completely inhibited at 70 mM ,while the same concentration did not inhibit the growth of  Proteus mirabilis ,streptococcus mutans, Klebsiella pneumoniae and streptococcus pneumonia .after 24 h incubating in the present study we evaluate that 70 mM considered as the minimum inhibitory concentration.

Key words: Acetic acid, Acetic acid derivatives 2-(2- HP-AA) , Antibacterial effect , Cytoplasmic PH