Biochemical Changes in Fibroid Patients

Abstract

Some biochemical parameters were determined in sixty fibroid patients in University Teaching Hospital. Mean value for plasma total cholesterol (5.56±3.25mmol/L), Triglycerides (1.14±0.61mmol/L, Sodium(Na+) (140±3.0mmol/L), Chloride(CI-)(106±4.2mmol/L) Calcium(Ca2+)(2.5±0.17mmol/L), and Phosphorus(P)(1,40±0.3mmol/L) showed an increase when compared with the control. Analysis of the result showed a decrease in the mean value of total protein(6.01±0,15g/dL), Albumin(4.01± 6.25g/dL), Potassium(K)(3.64±o.32mmol/L) when compared with the control. The mean value of  bicarbonate(HCO3) (24.0±2.3mmol/L) was significantly higher (P<0.05) when compared with the control. The raised level of cholesterol and triglycerides in fibroid patient reveal a possible link between fibroid and hypertension while increase concentration of Ca2+,Mg²+ and low concentration of K+ characterise increase oestrogen level which has been implicated in fibroid growth.

Keywords: Total cholesterol, triglycerides, total protein, Albumin, fibroid.