Ultrasound Irradiated High-Speed Classical Synthesis and Biological Studies of Various N-Substituted Phthaloyl Derivatives

Abstract

Ultrasound irradiation high-speed and classical synthesis of various N-substituted phthaloyl derivatives as potent bactericidal agents are described. All compound show antibacterial activities when compared with standard drugs.A series of various N-substituted phthaloyl derivatives have been synthesized in a very good yield under irradiation conditions (ultrasound irradiation high-speed) and conventional heat. All compound show antibacterial activities when compared with standard drugs. All compounds have been characterized by IR, ¹H NMR and ¹³C NMR.

Keywords: phthalymide, phthalimido dimer, phthalic anhydride, ultrasound irradiation, high-speed synthesis.