N – Methyl thiomethylation and N-Hydroxymethylation of Phthalimide

N.D. Zargar, K.Z. Khan

Abstract


N- Methyl thiomethyl phthalimide (I) a new compound was obtained when phthalimide was refluxed with DMSO acetic anhydride  reagent and DMSO alone at 180oC. A different route for the synthesis of N- Hydroxy methylphthalilmide (II)with excellent yield has also been explored by this reaction.

Key Words: DMSO, Acetic anhydride, Phthalimide, Methyl thiomethylation


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ISSN (Paper)2224-3224 ISSN (Online)2225-0956

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