Synthesis, Characterization and Antibacterial Activity of Some New 5,5'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-3,3'-bipyrazole Derivatives

Abstract

An efficient and practical synthesis of five compounds of pyrazoline derivatives structures was achieved through cyclization of hydrazine hydrate with 1,6-diphenylhexa-1,5-diene-3,4-dione using glacial acetic acid as catalyst under thermal conditions. These compounds have been characterized by FT-IR, elemental analysis (C.H.N.) and ¹H NMR spectroscopy.

Keywords:pyrazoline, chalcone, heterocyclic