Chemistry and Materials Research
Preparation and Spectroscopic Study of the Reaction of 4-Nitroacetophenone , Furfural and Thiourea
Abstract
The Chalcone (1) were prepared by Claisen –Schmidt condensation of 4-nitroacetophenone with furfural in presence of sodium hydroxide and ethanol. This chalcone were treated with thiourea, guanidine hydrochloride to yield the respective pyrimidine derivative.
The synthesized compounds were characterized by UV, IR, 1H-NMR & 13C-NMR spectral data.
Keywords: Chalcones, Furfural, 4-nitroacetophenone,.
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ISSN (Paper)2224-3224 ISSN (Online)2225-0956
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