The Effect of NADPH in the Oxidization of Benzidine in the H2O2 / Peroxidase System

Ebrahim Naif Ismail

Abstract


The carcinogenic chemicals are divided into two group:

The first group: it is effective in cancer and does not require pre-activation, such as alkaline agents.

The second group: their number is larger than the first group and need to be activated before they become carcinogenic, such as aromatic amines.

When entering the organism, the chemical compounds are subject to the effect of enzymes, especially oxidation enzymes such as oxygenases and Peroxidases. In the Peroxidase oxidation of aromatic amines are oxidized

And the amino group is transformed into an imino group.


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ISSN (Paper)2224-3224 ISSN (Online)2225-0956

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