Synthetic, Spectroscopic And Antibacterial Studies Of Fe(II),Co(II),Ni(II),Cu(II),and Zn(II)Mixed Ligand Complexes Of Nicotinamide And Cephalexin antibiotics

Abstract

Mixed  ligand complexes of bivalent metal  ions, viz; M= Co(II), Ni(II), Cu(II) and Zn(II) of  the composition [M(Ceph)(NA)₃]Cl  in 1:1:3  molar  ratio,  (where  Ceph = Cephalexin  and NA = Nicotinamide have  been  synthesized and  characterized  by  repeated  melting  point  determination, Solubility, Molar conductivity, determination  the percentage of  the metal  in  the  complexes  by  flame(AAS),  FT-IR, magnetic  susceptibility  measurements  and  electronic  spectral  data.  The   ligands and  their metal complexes were  screened  for  their antimicrobial activity against  six bacteria(gram +ve) and (gram -ve).

Key words:(Cephalexin antibiotics,Nicotinamide ,mixed ligand) Complexes,Antibacterial activities, and spectral studies