Nucleoside analogues synthesis using natural phosphate doped with I2 (NP/I2) in HMDS

Driss Ouzebla, Hassan B. Lazrek, Michael Smietana, Jean-Jacques Vasseur

Abstract


Several D-ribonucleosides are prepared from1-O-acetyl-2,3,5-tri-O-benzoyl-?-D-ribofuranoside and trimethylsilylated nucleobases under mild conditions by using natural phosphate doped with I2 as catalyst Keywords: Natural Phosphate doped with I2, one-step seynthesis. ?/?-D-ribonucleosides


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ISSN (Paper)2224-3224 ISSN (Online)2225-0956

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