MoO3-SiO2 as an efficient and reusable heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles

Abstract

An efficient method for the preparation of 5-substituted 1H-tetrazole derivatives is reported using MoO₃-SiO₂ as an efficient heterogeneous catalyst. This method has the advantages of high yields, simple methodology and easy work-up. This catalyst could be recycled

An efficient method for the preparation of 5-substituted 1H-tetrazole derivatives is reported using MoO₃-SiO₂ as an efficient heterogeneous catalyst. This method has the advantages of high yields, simple methodology and easy work-up. This catalyst could be recycled very easily, which makes this methodology environmentally benign.

Keywords: 5-substituted 1H-tetrazole, [2+3] cycloaddition, MoO₃-SiO₂, solid acid