Correlation between Leptin Encoding Gene and Some Haematological and Biochemical Parameters in Awassi Sheep

Abstract

The present study was scanned 104 of different genotypic Iraqi Awassi sheep to determine the relation of genetic polymorphism for leptin gene with several biochemical and haematological features. The results of this study were revealed that most of blood characters were homologous for the genotypes AA, AB, AH, AM, AR, and AS except for RBCs and WBCs count since there were significant differences (P< 0.05) between them, and the following genotypes AH and AB were surpassed on the two genotypes AM and AB concerning the number of RBCs, and the two genotypes AB and AH were surpassed on the genotype AM concerning the number of WBCs. Most of biochemical characters were nonhomologous except for the concentration of urea, since significant differences (P< 0.05) among the genotypes were observed with respect to glucose, protein, cholesterol, and triglycerides. The AH genotype was surpassed the two genotypes AB and AR concerning the glucose ratio. The AB genotype was surpassed the two genotypes AM and AS, the two genotypes AA and AH were surpassed the AB genotype concerning cholesterol ratio, and the AB genotype was surpassed the AH genotype concerning the level of triglyceride. In conclusion, the leptin gene diagnostic tool could be used for selection process to enhance the production levels in Awassi sheep through eliminating the animals that were correlated with the genotypes of some undesired characters in early breeding times.

Keywords; leptin, gene, Awassi, parameter, blood, biochemistry