Effect of Vitamin D Supplementatiton Against of Periodontal Pocket Depth Changes and Clinical Attachment Loss in Healing Process of Chronic Periodontitis Disease

Abstract

Introduction: Vitamin D can be beneficial in the treatment of chronic periodontitis as an antibacterial and antiinflamation effect. Its act to elliminate periodontopatogen bacterial and inhibit the release of proinflammatory mediators by immunomodulator action of innate and adaptif immunity to resolve the inflamatory process of the periodontal disease. This study was aimed to evaluate the effect of vitamin D suplementation towards the levels of vitamin D in the blood, as well as to determine periodontal pocket depth (PPD), and clinical attachment loss (CAL) in healing process on chronic periodontitis disease. Material & Methods: A total of 45 individuals of chronic periodontitis were colected and randomized divided into three  groups. vitamin D suplementation (placebo, 5,000 IU and 10,000 IU) was gave blindly one tablet per week within 6 weeks to all of the subject after received scaling and root planing (SRP) treatment. All the measurement like periodontal clinical parameters using a periodontal probe and serum vitamin D levels using the ELISA (Enzyme Linked Immunosorbent Assay) technique were noted before and after SRP treatment. Results: the results showed that there were significant differences of all clinical periodontal parameters in each treatment group compare to placebo group (p < 0.05) but between 5,000 IU and 10,000 IU group showed that there were no significant different (p>0.05). Conclusion: Vitamin D suplementation at 5,000 IU can supported in chronic periodontitis treatment which provide a new direction in management of periodontal treatment and healing process more rapidly.

Keywords: Chronic Periodontitis; Vitamin D Suplementation ; CAL ; PPD