Cell Growth Factors

Abstract

My study’s importance is evaluate the structural properties of cell growth factors (GFs) their functions in interactions among cells based on these properties. Glycoproteins synthesized by the effect of genes bound to receptors on the cell surface and stored in the extracellular matrix are called as growth factors. Growth factors, unlike hormones, can be excreted by many cells. These factors can stimulate or suppress cell division, differentiation, migration, or genetic activities by affecting cellular activity. They also help hematopoietic stem cells to transform into blood cells. These growth factors can work in the cell by binding only to an appropriate receptor. According to the structural characteristics, they are divided into eight categories: vascular endothelial growth factor, epidermal growth factor, fibroblast growth factors, platelet - derived growth factor, transforming growth factor, insulin - like growth factor, hematopoietic growth factor, and nerve growth factor. Today these growth factors have been used for preparing wound - burn cover materials, removing skin wrinkles, controlling cholesterol levels, strengthening immune system, and developing healthier hair and nails. These factors can be used in treating many diseases, particularly cancer, repair of damages on nerve tissues, dwarfism therapy, and deceleration or interception of cell aging. In addition, attempts are being made to develop new systems for the most effective and efficient use of these growth factors.

Keywords: Biotechnology, Anti - aging of cells, Treatment of neuron damage, Treatment of wound burn, Apoptosis.