Community-Acquired Urinary Tract Infection (Etiology and Bacterial Susceptibility)

Abstract

Objectives: The aim of this study was to report the prevalence of uropathogens and their antibiotic susceptibility of the community acquired UTI diagnosed in our institution and to provide a national data.
Methods: We analyzed retrospectively the results of urine cultures of 416 patients that had community acquired urinary tract infection and had urine sampled in the Central Laboratory of the Ministry of Health in Amman the capital of Jordan, January to June of 2011.  Results: The most commonly isolated organism was Escherichia coli (70%). ?-Hemolytic Streptococcus group B (8%) and Klebsiella sp (7.6%) were reported as the next most common organisms. Of all bacteria isolated from community acquired UTI, only 21% were sensitive to ampicillin, 23% to ciprofloxacin and 18% to cotrimoxazole. The highest levels of susceptibility were to cephalothin (81%), Gentamicin (40 %), Augmentin (33%),  Norfloxacin (28%), Nitrofurantion (23%), Lefloxacin (21%), Nalidixic acid (16%), Imipenem (14%). Conclusion: Gram-negative agents are the most common cause of UTI. Cephalothin remains the choice among the orally administered antibiotics, followed by Gentamicin, Augmentin. For severe disease causes by Escherichia coli which is the most common cause community acquired UTI that require antibiotics such as nitrofurantion, followed by third generation cephalosporins, which were the most effective.

Keywords: Urinary tract; Infection; Community; Bacteria; Antibiotic; Susceptibility.