Reproductive Hormones and Fibroid Cases in Nigerian Women

Abstract

Investigations were carried out on the association between some reproductive hormones (Progesterone, oestrogen, leutenizing and follicle stimulating hormones), and fibroid cases in Nigerian women.  The levels of these hormones were determined in 30 patients with chronic fibroid cases and another 30 patients with non chronic fibroid cases. The mean values of these hormones in non-chronic fibroid cases (14.50±0.20, 98.01±0.67, 0.51±0.05, 4.02±0.74 respectively), were found  to be significantly higher than corresponding values in non fibroid cases. Also the values obtained in chronic fibroid cases were also significantly higher (P<0.05) than that of the non chronic fibroid cases. Our finding indicates that the alteration in these reproductive hormone levels might be related with the pathogenesis of fibroid in Nigerian women.

Keywords: reproductive hormones, progesterone, oestrogen, leuteinizing hormones, follicle stimulating hormones, fibroid, pathogenesis.